Tuolumne Road was cleared about an hour after a traffic collision, and officials say alcohol was a likely factor in the wreck.
Just after 3:30pm Thursday, a collision and vehicle fire were reported at Tuolumne Road and Woodham Carne.
Reports said the suspect in the case, described as a white male, had initially fled the scene on foot.
Emergency vehicles were blocking the road as crews were dealing with two more victims who were injured in the wreck. The roadway was reported clear about 4:20pm.
Additional reports indicated the suspect was taken to Tuolumne General Hospital, where he was reportedly being combative.
Sonora Police units responded to assist, and the situation was finally said to be under control an hour after the inital calls were dispatched.